TargetMol

Ro 41-1049 hydrochloride

Product Code:
 
TAR-T16770
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
CAS:
127917-66-2
Formula:
C12H13ClFN3OS
Molecular Weight:
301.76
Pathway:
Metabolism; Neuroscience
Purity:
0.98
SMILES:
Cl.NCCNC(=O)c1ncsc1-c1cccc(F)c1
Target:
MAO

References

1. Cesura AM, et al. Characterization of the binding of [3H]Ro 41-1049 to the active site of human monoamine oxidase-A. Mol Pharmacol. 1990 Mar;37(3):358-66. 2. Brannan T, et al. Effect of a selective MAO-A inhibitor (Ro 41-1049) on striatal L-dopa and dopamine metabolism: an in vivo study. J Neural Transm Park Dis Dement Sect. 1994;8(1-2):99-105.