TargetMol

Thyroxine sulfate

Product Code:
 
TAR-T20557
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Thyroxine sulfate is a sulfoconjugated derivative of Thyroxine and is also a metabolite of Thyroxine.
CAS:
77074-49-8
Formula:
C15H11I4NO7S
Molecular Weight:
856.93
Purity:
0.98
SMILES:
N[C@@H](Cc1cc(I)c(Oc2cc(I)c(OS(O)(=O)=O)c(I)c2)c(I)c1)C(O)=O

References

1. Manna D, Mondal S, Mugesh G. Halogen bonding controls the regioselectivity of the deiodination of thyroid hormones and their sulfate analogues. Chemistry. 2015 Feb 2;21(6):2409-16. doi: 10.1002/chem.201405442. Epub 2014 Dec 8. PubMed PMID: 25487845. 2. Huang WS, Cherng SC, Wang CH, Shih BF, Kuo SW, Wu SY. Increased urinary thyroxine sulfate excretion in thyroxine therapy. Endocr J. 1997 Aug;44(4):467-72. Erratum in: Endocr J 1997 Oct;44(5):following 764. PubMed PMID: 9447277. 3. Wu SY, Huang WS, Polk D, Florsheim WH, Green WL, Fisher DA. Identification of thyroxine-sulfate (T4S) in human serum and amniotic fluid by a novel T4S radioimmunoassay. Thyroid. 1992 Summer;2(2):101-5. PubMed PMID: 1525576. 4. Peeters RP, Kester MH, Wouters PJ, Kaptein E, van Toor H, Visser TJ, Van den Berghe G. Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type I deiodinase activity. J Clin Endocrinol Metab. 2005 Dec;90(12):6460-5. Epub 2005 Sep 27. PubMed PMID: 16189257.