TargetMol

Benazepril

Product Code:
 
TAR-T20921
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20921-10mg10mg£230.00
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Further Information

Bioactivity:
Benazepril inhibits the activity of circulating angiotensin-converting enzyme (ACE) in horses.
CAS:
86541-75-5
Formula:
C24H28N2O5
Molecular Weight:
424.5
Purity:
0.98
SMILES:
O=C(O)CN1C([C@@H](N[C@@H](CCC2=CC=CC=C2)C(OCC)=O)CCC3=CC=CC=C31)=O

References

1. Serrano-Rodr?guez JM, G?mez-D?ez M, Esgueva M, Castej?n-Riber C, Mena-Bravo A, Priego-Capote F, Ayala N, Caballero JMS, Mu?oz A. Pharmacokinetic/pharmacodynamic modeling of benazepril and benazeprilat after administration of intravenous and oral doses of benazepril in healthy horses. Res Vet Sci. 2017 Oct;114:117-122. doi: 10.1016/j.rvsc.2017.03.016. Epub 2017 Mar 28. PubMed PMID: 28371693. 2. King JN, Font A, Rousselot JF, Ash RA, Bonfanti U, Brovida C, Crowe ID, Lanore D, Pechereau D, Seewald W, Strehlau G. Effects of Benazepril on Survival of Dogs with Chronic Kidney Disease: A Multicenter, Randomized, Blinded, Placebo-Controlled Clinical Trial. J Vet Intern Med. 2017 Jul;31(4):1113-1122. doi: 10.1111/jvim.14726. Epub 2017 Jul 1. PubMed PMID: 28669137; PubMed Central PMCID: PMC5508345. 3. Afonso T, Gigu?re S, Rapoport G, Brown SA, Coleman AE. Attenuation of the blood pressure response to exogenous angiotensin I after oral administration of benazepril to healthy adult horses. Equine Vet J. 2017 May;49(3):358-362. doi: 10.1111/evj.12593. Epub 2016 Jul 11. PubMed PMID: 27224673. 4. King JN, Panteri A, Graille M, Seewald W, Friton G, Desevaux C. Effect of benazepril, robenacoxib and their combination on glomerular filtration rate in cats. BMC Vet Res. 2016 Jun 23;12(1):124. doi: 10.1186/s12917-016-0734-4. PubMed PMID: 27338786; PubMed Central PMCID: PMC4917992.