TargetMol

Ceftizoxime Sodium

Product Code:
 
TAR-T21386
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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Further Information

Bioactivity:
Ceftizoxime, a third-generation cephalosporin effective against Gram-negative and Gram-positive bacteria, binds penicillin-binding proteins (PBPs) to inhibit the bacterial cell wall synthesis. It rather resembles cefotaxime in its properties but is not subject to metabolism.
CAS:
68401-82-1
Formula:
C13H12N5NaO5S2
Molecular Weight:
405.38
Purity:
0.98
SMILES:
[Na+].CON=C(/C(=O)NC1C2SCC=C(N2C1=O)C([O-])=O)c1csc(N)n1

References

1. T?rke? C, S?y?t H, Beydemir ?. Human serum paraoxonase-1 (hPON1): in vitro inhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium. J Enzyme Inhib Med Chem. 2015;30(4):622-8. doi: 10.3109/14756366.2014.959511. Epub 2014 Dec 18. PubMed PMID: 25519764. 2. Bharathi Ch, Prasad ChS, Bharathi DV, Shankar R, Rao VJ, Dandala R, Naidu A. Structural identification and characterization of impurities in ceftizoxime sodium. J Pharm Biomed Anal. 2007 Jan 17;43(2):733-40. Epub 2006 Sep 6. PubMed PMID: 16950586. 3. Nahata MC, Edmonds JJ, Morosco RS. Stability of metronidazole and ceftizoxime sodium in ready-to-use metronidazole bags stored at 4 and 25 degrees C. Am J Health Syst Pharm. 1996 May 1;53(9):1046-8. PubMed PMID: 8744468. 4. Rivers TE, Webster AA. Stability of ceftizoxime sodium, ceftriaxone sodium, and ceftazidime with metronidazole in ready-to-use metronidazole bags. Am J Health Syst Pharm. 1995 Nov 15;52(22):2568-70. PubMed PMID: 8590243.