TargetMol

Yohimbine

Product Code:
 
TAR-TCS2185
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM)
CAS:
146-48-5
Formula:
C21H26N2O3
Molecular Weight:
354.45
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCc3c1[nH]c1ccccc31)C2
Target:
Adrenergic Receptor

References

Vay M, Sauter M, Mikus G,et al.Quantification of microdosed oral yohimbine and its major metabolite in human plasma in the picogram range[1].Bioanalysis. 2019 Aug;11(16):1459-1467. Williams K L , Nickel M M , Bielak J T . Baclofen Blocks Yohimbine-Induced Increases in Ethanol-Reinforced Responding in Rats[J]. Pharmacology Biochemistry & Behavior, 2016:S0091305716300223.