TargetMol

Adenine monohydrochloride hemihydrate

Product Code:
 
TAR-T5081
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T5081-1g1g£103.00
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Quantity:
TAR-T5081-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
Adenine is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor and also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively).
CAS:
6055-72-7
Formula:
C5H8ClN5O
Molecular Weight:
189.6
Pathway:
Metabolism; Neuroscience; GPCR/G Protein
Purity:
0.9761
SMILES:
O.Cl.Nc1ncnc2nc[nH]c12
Target:
Endogenous Metabolite; Adenosine Receptor

References

Bender E, et al. Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8573-8. Gorzalka S, et al. Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. Mol Pharmacol. 2005 Mar;67(3):955-64.