Leinco Technologies

Recombinant Rat CNTF

Product Code:
 
LEI-C329
Product Group:
 
Recombinant Proteins
Host Type:
 
Rat
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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CodeSizePrice
LEI-C329-10ug10 ug£352.00
Quantity:
LEI-C329-50ug50 ug£853.00
Quantity:
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This product comes from: US.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Ciliary neurotrophic factor (CNTF) is a cytokine1 that supports survival and/or differentiation of a variety of neuronal cell types including sensory, sympathetic, and motoneurons.2 With these abilities, CNTF has implications for Parkinson's disease and cell-replacement therapies for other disorders.3 CNTF mimics the biological actions of leptin while overcoming "leptin resistance" and appears to reduce inflammatory signaling cascades associated with lipid accumulation in liver and skeletal muscle. The advantages and disadvantages of CNTF has shown promise as a therapeutic strategy to alleviate obesity-associated diseases.4
NCBI Gene:
25707
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
CNTF

References

1. Boschero, AC. et al. (2009) Cytokine46(1):65-71. 2. Thoenen, H. et al. (1994) J Neurobiol. 25: 1436 3. Hagg, T. et al. (2008) J Neurosci. 28: 2231 4. Febbraio, MA. et al. (2008) J Mol Med. 86: 353