Leinco Technologies

Recombinant Human TRAIL/Apo2L

Product Code:
 
LEI-T164
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-T164-10ug10 ug£614.00
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This product comes from: US.
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Further Information

Format:
Lyophilized from a 0.2 um filtered solution in Tris, (NH4)2SO4 and ZnSO4.
Formulation:
Lyophilized from a 0.2 um filtered solution in Tris, (NH4)2SO4 and ZnSO4.
Long Description:
TRAIL/Apo2L is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic ?death domain,? which activates the cell's apoptotic machinery. Recombinant human soluble TRAIL/Apo2L is a 168 amino acid polypeptide (19.6 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL/Apo2L protein.
Purity:
>97% by SDS-PAGE and HPLC
Target:
TRAIL

References

1. Rehm, M. et al. (2008) Biochim Biophys Acta. 1783(10):1903-13. Article Link