Leinco Technologies

Recombinant Human TWEAK

Product Code:
 
LEI-T169
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-T169-25ug25 ug£614.00
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) with BSA as a carrier protein. pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) with BSA as a carrier protein. pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF superfamily. This cytokine has overlapping signaling functions with TNF but displays a much wider tissue distribution. TWEAK is expressed in a variety of tissues, including the adult heart, pancreas, skeletal muscle, small intestine, spleen and peripheral blood lymphocytes. (1). It has pleiotropic biological functions including proapoptotic, proangiogenic and proinflammatory activities (2-3). TWEAK also induces skeletal muscle atrophy (4). It can function as both as a type II transmembrane protein and as a cleaved soluble protein. TWEAK is the ligand for the FN14/TWEAKR receptor.
NCBI Gene:
8742
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
TWEAK

References

1. Aaron, JW. et al. (2006) Molecular Endo. 20:2528 2. Burkly, LC. et al. (2005) Oncogene 24:2613 3. Young, S. et al. (2003) Biochem. Biophys. Res. Commun. 305:789 4. Kumar, A. et al. (2007) FASEB J. 21:1857