Leinco Technologies

Anti-Human ICAM-1 (Clone 15.2) - Biotin

Product Code:
 
LEI-C168
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
15.2
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Ambient
Storage:
 
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
 

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CodeSizePrice
LEI-C168-50ug50 ug£152.00
Quantity:
LEI-C168-100ug100 ug£209.00
Quantity:
LEI-C168-200ug200 ug£303.00
Quantity:
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Further Information

Antigen Distribution:
ICAM-1 is a membrane glycoprotein with a wide tissue distribution that includes vascular endothelium and many cells of the immune system. CD54 is weakly expressed on resting peripheral blood lymphocytes. Upon activation by mitogens, the CD54 antigen is strongly expressed on B-cells, T-cells, macrophages and granulocytes. CD54 is the receptor for rhinoviruses and malaria.1
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen:
Purified Recombinant Human ICAM-1 (>98%)
Long Description:
Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein1 and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.2 ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.3
NCBI Gene:
3383
Target:
Inter-Cellular Adhesion Molecule 1

References

1. Li S et al. (2009) Biochem Biophys Res Commun. 381: 459 2. Wolf S et al. (2009) Pharmacol Rep 61: 22 3. Ozcan U et al. (2009) Arch Gynecol Obstet.