Leinco Technologies

Anti-Human Prolactin

Product Code:
 
LEI-P283
Product Group:
 
Primary Antibodies
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Neutralisation
  • Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
 

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CodeSizePrice
LEI-P283-25ug25 ug£420.00
Quantity:
LEI-P283-100ug100 ug£694.00
Quantity:
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This product comes from: US.
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Further Information

Conjugate/Tag/Label:
Antigen Affinity Purified
Format:
This antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.4 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Formulation:
This antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.4 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Immunogen:
Purified Recombinant Human PRL (>98%)
Long Description:
Prolactin (PRL) or Luteotropic hormone (LTH) is best known as the pituitary modulator of lactation and reproduction.1 Prolactin is a multifaceted hormone that is capable of modulating hundreds of physiological processes in adult vertebrates.2 PRL promotes proliferation, survival and migration of cancer cells acting via the prolactin receptor (PRLR).3 It also modulates maternal behavior and mediates hypothalamic pituitary adrenal axis inhibition during lactation via PRL receptors in the brain.4 Prolactin also has a number of other effects including contributing to surfactant synthesis of the fetal lungs at the end of the pregnancy and immune tolerance of the fetus by the maternal organism during pregnancy. It also decreases normal levels of sex hormones ? estrogen in women and testosterone in men.5
NCBI Gene:
5617
Target:
Prolactin

References

1. Paus, R. et al. (2012) Arch Dermatol Res. 304(2):115-8. 2. Zhu, Y. et al. (2008) Comp Biochem Physiol C Toxicol Pharmacol. 148(4):370-80.3. Panina, S. et al. (2009) J Endocrinol. 201(1):115-28.4. Neuwmann, ID. et al. (2009) Endocrinology. 150(4):1841-9.5. Molitch MD., ME. (2005) Mayo Clinic Proceedings 80(8):1050-10576. Gout, PW. et al. (1980) Cancer Research 40:2433-36.