Leinco Technologies

Recombinant Human TROP-2

Product Code:
 
LEI-T404
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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LEI-T404-100ug100 ug£637.00
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This product comes from: US.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.4 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.4 with no calcium, magnesium, or preservatives.
Long Description:
Trop-2 is a cell surface glycoprotein1 that is highly expressed in a wide variety of epithelial cancers. There is little or no expression of Trop-2 in adult somatic tissue.2 Trop-2 is a novel calcium signal transducer3 involved in the regulation of cell- cell adhesion.4 It is an oncogene that has potential as a therapeutic target.2 It is a possible candidate gene for diagnosis and molecular target therapy of colorectal cancer.5
NCBI Gene:
4070
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
TROP-2

References

1. Colnaghi, MI. et al. (1992) Hybridoma 11: 539 2. Michel, L. et al. (2008) Mol Cancer Ther. 7: 280 3. Alberti, S. et al. (1998) Int J Cancer 75: 324 4. Piantelli, M. et al. (2007) J Clin Oncol. 25: 10510 5. Mori, M. et al. (2006) clin Cancer Res. 12: 3057