Leinco Technologies

Human TL-1A ELISA Development Kit

Product Code:
 
LEI-T516
Product Group:
 
ELISA Kits
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
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LEI-T516-5plates5 plates£637.00
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Further Information

Long Description:
TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.1 TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.2
Target:
TNF-Ligand-Related Molecule 1-A

References

1. Wei P et al. (2003) J Biol Chem. 278: 39251 2. Fabio Cominelli et al. (2006) PNAS 103: 8441