Leinco Technologies

Anti-Mouse ICOS (Clone C398.4A) - Purified (PhenoCycler-Fusion (CODEX)® Ready)

Product Code:
 
LEI-I-2012
Product Group:
 
Primary Antibodies
Host Type:
 
Hamster
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
C398.4A
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Spatial Biology
Storage:
 
This antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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LEI-I-2012-50ug50 ug£167.00
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This product comes from: US.
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Further Information

Antigen Distribution:
ICOS is expressed on activated T cells and APCs including splenic B cells, dendritic cells, and macrophages.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
PhenoCycler®, Purified (PhenoCycler® Ready)
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4.
Immunogen:
Human Retinoblastoma tumor
Long Description:
CD278 (ICOS) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers (47-57kD) and enhances all basic T cell responses to a foreign antigen, specifically proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. ICOS signaling is also an important regulator for T cell homeostasis. ICOS plays a role in humoral immune response and is thought to have involvement in the development of Th2 cells and to play a protective role in inflammatory autoimmune diseases.
Target:
ICOS