Anti-M6a (Mouse) mAb

FCM - 5-10 ug/mL (final concentration) IHC - 1-10 ug/mL This antibody is suitable for use on frozen sections.

M6 is a membrane glycoprotein that is abundantly expressed on central neurons in the CHS. Two distinct murine M6 cDNA (designated M6a and M6b) whose deduced amino acid sequences are remarkably similar to that of the major CNS myelin protein PLP/DM20 are known. PLP expression is limited to the white matter. M6a appears in post-mitotic neurons of the brain and spinal cord as early as embryonic day 10, and later in the hIPocampus, cerebral cortex, and the granule cells of the cerebellum. In contrast, M6b is expressed at early embryonic stage in the ventricular zone of the spinal cord, and later during development in both neurons and glia.

1 mg/mL

100ug IgG in 100ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.

Human: 2823 Mouse: 234267

Mouse M6a-expressing cells

This antibody reacts with mouse M6a on flow cytometry.

1 year

This antibody was purified from nude mouse ascites (clone 321) supernatant using protein G agarose. This hybridoma was established by fusion of mouse myeloma cell P3X with Wister rat splenocyte immunized with mouse M6a expressing cells.

M6a