MBL

Anti-ELAVL1 (HuR) mAb

Product Code:
 
MBL-RN007M
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
C67-1
Regulatory Status:
 
RUO
Target Species:
  • Hamster
  • Human
  • Mouse
  • Rat
Applications:
  • Immunoprecipitation (IP)
  • RIP
  • Western Blot (WB)
Shipping:
 
4°C
Storage:
 
-20°C
1 / 6
2 / 6
3 / 6
4 / 6
5 / 6
6 / 6
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
MBL-RN007M200 ul£404.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Applications:
WB - 1 μg/mL IP - 1.5 μg/50 μL of cell extract from 1.65 x 106 cells/sample RIP - 15 μg/500 μL cell extract from 1.65 x 107 cells
Background:
ELAVL1/HuR, like other ELAVL proteins, has a short N-terminal region followed by 2 RNA-binding motifs, a basic linker domain, and a third RNA-binding motif. The basic hinge region bears a novel nuclear shuttling sequence which is implicated in the nucleocytoplasmic HuR shuttling. Unlike its neuron-specific ELAV relatives (HuB, HuC and HuD), HuR itself is ubiquitously expressed. Structure-function analyses of HuR have shown that it binds to AU-rich mRNA sequences in the nucleus and may be involved in their nuclear export.
Formulation:
PBS containing 50% Glycerol (pH 7.2)
Gene IDs:
Human: 1994 Mouse: 15568 Rat: 363854
Target:
ELAVL1 (HuR)

Documents

References

1) Ma, W. J., et al., J. Biol. Chem. 271, 8144-8151 (1996) 2) Fan, X. C., and Steitz, J. A., PNAS 95, 15293-15298 (1998) 3) Fan, X. C., and Steitz, J. A., EMBO J, 17, 3448-3460 (1998)