MBL

Anti-PTBP1 (Human) pAb

Product Code:
 
MBL-RN011P
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
Affinity Purified Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunocytochemistry (ICC)
  • Immunoprecipitation (IP)
  • RIP
  • Western Blot (WB)
Shipping:
 
4°C
Storage:
 
-20°C
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CodeSizePrice
MBL-RN011P200 ul£404.00
Quantity:
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  • Further Information
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Further Information

Applications:
WB - 1:1,000 IP - 5 ug/250 uL of cell extract from 2.5 x 106 cells RIP - 15 ug/500 uL of cell extract from 6 x 106 cells
Background:
The polypyrimidine tract binding protein 1 (PTBP1), a 57 kDa RNA binding protein also known as hnRNP1, has been implicated in multiple aspect of mRNA metabolism, including regulation of alternative splicing, internal ribosome entry site-driven translation, mRNA localization, and polyadenylation. Four of tandem RNA recognition motif domains give PTBP1 a strong binding activity to RNA. Posttranscriptional regulation of gene expression by PTBP1 has been reported on many genes, including CD154, insulin, VEGF and Human inducible nitric oxide synthase.
Concentration:
1 mg/mL
Formulation:
200 ul volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Gene IDs:
Human: 5725 Mouse: 19205
Immunogen Translated:
Peptide bond synthesis KFKGDSRSAGVPSR KLH (46-59 aa)
Reactivity:
This antibody reacts with human PTBP1 (~57 kDa) on Western blotting, Immunoprecipitation and RNP Immunoprecipitation.
Shelf Life:
1 year
Source:
This antibody was purified from rabbit serum by affinity column chro matography. The rabbit was immunized with KLH conjugated synthetic peptide, KFKGDSRSAGVPSR corresponding to 46-59 aa.
Target:
PTBP1

Documents

References

1) Porter, J. F., et al., J. Immunol. 181, 3336-3345 (2008) 2) Pautz, A., et al., J. Biol. Chem. 281, 32294-32302 (2006) 3) Cornelis, S., et al., Nucleic Acids Res. 33, 3095-3108 (2005)