MBL

Anti-CD25 (Mouse) mAb-FITC

Product Code:
 
MBL-FP20265002
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG1 λ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PC61.5
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP2026500225 ug£201.00
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Further Information

Background:
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor β) and CD 132 (IL-2 Receptor γc, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Rα. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
Concentration:
0.5 mg/mL
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD25

Documents

References

Marzio, R., et al., J Leukoc Biol. 62, 349-355 (1997) Yokoyama, W. M., et al., J Immunol. 141, 369-376 (1988) Sobel, E. S., et al., J Immunol. 150, 673-682 (1993)