MBL

Anti-IFN gamma (Mouse) mAb Functional Grade

Product Code:
 
MBL-FP20712510
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
XMG1.2
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Functional Study
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
 
4°C
Storage:
 
4°C
 

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CodeSizePrice
MBL-FP20712510100 ug£333.00
Quantity:
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This product comes from: United States.
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  • Further Information
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Further Information

Background:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells.The biological activity of IFN-γ is not affected by glycosylation.
Concentration:
2 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
IFN gamma

Documents

References

Knapp W., et al., Leukocyte typing IV. Oxford University Press (1989) Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Bullock, T. N., & Yagita, H., J Immunol. 174, 710-717 (2005)