MBL

Anti-IFN gamma (Mouse) mAb-PE

Product Code:
 
MBL-FP20716002
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
XMG1.2
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP2071600225 ug£215.00
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This product comes from: United States.
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Further Information

Background:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells.The biological activity of IFN-γ is not affected by glycosylation.
Concentration:
0.2 mg/mL
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
IFN gamma

Documents

References

Ridger, V. C., et al., J Immunol. 166, 3484-3490 (2001) Noto, K., et al., Int Immunol. 7, 835-842 (1995) Sangaletti, S., et al., Cancer Res. 68, 9050-9059 (2008)