MBL

Anti-Foxp3 (Mouse) mAb-PE

Product Code:
 
MBL-FP20836010
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MF23
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP20836010100 ug£603.00
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Further Information

Background:
The MF23 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression. Mutations of Foxp3 result in the ?scurfy? mice phenotype. It is reported that the MF23 antibody recognizes an epitope between 1-87 amino acids in the N-terminal domain of mouse Foxp3.
Concentration:
0.2 mg/mL
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
Foxp3

Documents

References

Norton, A. J., & Isaacson, P. G., Am J Pathol. 128, 225-240 (1987) Hua, Z. X., et al., Hum Pathol. 29, 1441-1446 (1998) Ioachim, H. L., et at., Am J Surg Pathol. 20, 64-71 (1996)