MBL

Anti-Fc epsilon Receptor I alpha (FceR1) (Mouse) mAb Functional Grade

Product Code:
 
MBL-FP20842510
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Hamster
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
41699
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Functional Study
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP20842510100 ug£347.00
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  • Further Information
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Further Information

Background:
The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo.
Concentration:
2 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
Fc epsilon Receptor I alpha

Documents

References

Barclay, A., et al., The leucocyte antigen factsbook. Academic Press, London (1997) Pulendran, B., et al., J Immunol. 159, 2222-2231 (1997) Xin, K. Q., et al., J Virol. 80, 11899-11910 (2006)