Elabscience

Recombinant Mouse Angiotensin-Converting Enzyme 2/ACE-2 (C-10His)

Product Code:
 
PKSM041433
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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CodeSizePrice
PKSM041433-10ug10ug£264.00
Quantity:
PKSM041433-50ug50ug£639.00
Quantity:
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Further Information

Abbreviation:
ACE2;ACE-2
Accession:
Q8R0I0
Background:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don?t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Calculated MW:
84.9 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 25mM Tris-HCl, 150mM NaCl, 1mM ZnCl2, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-10His
ObservedMW:
85-110 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln18-Thr740
Target Synonym:
Angiotensin-Converting Enzyme 2;ACE-Related Carboxypeptidase;Angiotensin-Converting Enzyme Homolog;ACEH;Metalloprotease MPROT15;ACE2
UNIProt ID:
Q8R0I0

Documents