Elabscience

Recombinant Human CD68/SR-D1 (C-Fc)

Product Code:
 
PKSH034029
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSH034029-10ug10ug£207.00
Quantity:
PKSH034029-50ug50ug£466.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD68;SR-D1
Accession:
P34810
Background:
CD68, also called Scavenger Receptor D1 (SR-D1) and LAMP-4, is a heavily glycosylated type I transmembrane glycoprotein that belongs to the LAMP family. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. CD68 is also a biomarker of rheumatoid arthritis and Hodgkin's lymphoma. CD68 influences the functions of cells through NF-kB/focal adhesion kinase pathway (7). In addition, CD68 on macrophages binds tightly to both S100A8 and S100A9 to enhance the cell immunity.
Calculated MW:
58.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
70-100 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asn22-Ile320
Target Synonym:
CD68 antigenmacrophage antigen CD68;CD68 molecule;CD68;gp110;Macrosialin;SCARD1;SRD1;SR-D1
UNIProt ID:
P34810

Documents