Elabscience

P Glycoprotein Polyclonal Antibody

Product Code:
 
E-AB-65970
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Immunofluorescence (IF)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 2
Immunofluorescence analysis of C6 cells using P Glycoprotein Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
2 / 2
Immunofluorescence analysis of NIH/3T3 cells using P Glycoprotein Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
❮❯

Immunofluorescence analysis of C6 cells using P Glycoprotein Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of NIH/3T3 cells using P Glycoprotein Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-65970-60uL60uL£210.00
Quantity:
E-AB-65970-120uL120uL£291.00
Quantity:
E-AB-65970-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
P Glycoprotein
Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human P Glycoprotein (NP_000918.2).
Purification method:
Affinity purification
Target Synonym:
ABC20;CD243;CLCS;GP170;MDR1;P-GP;PGY1;P Glycoprotein;ABCB1
UNIProt ID:
P08183

Documents