Elabscience

APC Anti-Mouse CD105 Antibody[MJ7/18]

Product Code:
 
E-AB-F1233E
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clone:
 
MJ7/18
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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Mouse endothelial cells (bEnd.3) are stained with APC Anti-Mouse CD105 Antibody (filled gray histogram).APC Mouse IgG2a, κ Isotype Control stained cells are used as control.
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Mouse endothelial cells (bEnd.3) are stained with APC Anti-Mouse CD105 Antibody (filled gray histogram).APC Mouse IgG2a, κ Isotype Control stained cells are used as control.

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CodeSizePrice
E-AB-F1233E-50Tests50Tests£133.00
Quantity:
E-AB-F1233E-100Tests100Tests£174.00
Quantity:
E-AB-F1233E-100Testsx2100Testsx2£224.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD105
Background:
CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
APC
GeneID:
13805
Target Synonym:
Endoglin;END;Eng;
UNIProt ID:
Q63961
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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