Elabscience

AF/LE Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]

Product Code:
 
E-AB-F11920
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clone:
 
RMT3-23
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Blocking
  • Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C. Do not freeze.
 

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CodeSizePrice
E-AB-F11920-50ug50ug£140.00
Quantity:
E-AB-F11920-500ug500ug£341.00
Quantity:
E-AB-F11920-1mg1mg£475.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
CD366/Tim-3
Background:
CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Buffer:
0.2 um filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration:
0.5 mg/mL
Conjugation:
None (Purified antibody-Azide Free/Low endotoxin)
GeneID:
84868
Target Synonym:
TIM3; TIMD3;HAVcr-2;TIMD-3;
UNIProt ID:
Q8VIM0
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 2.0 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

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