Elabscience

PFKFB3 Polyclonal Antibody

Product Code:
 
E-AB-19543
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of 293T A549 A431 Hela and Jurkat cell lysates using PFKFB3 Polyclonal Antibody at dilution of 1:400
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Western blot analysis of 293T A549 A431 Hela and Jurkat cell lysates using PFKFB3 Polyclonal Antibody at dilution of 1:400

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E-AB-19543-20uL20uL£125.00
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E-AB-19543-60uL60uL£172.00
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E-AB-19543-120uL120uL£237.00
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E-AB-19543-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
PFKFB3
Background:
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
60 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PFKFB3
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Renal Carcinoma Antigen NY-REN-56;PFK/FBPase 3;IPFK2;PFK2
UNIProt ID:
Q16875

Documents