Elabscience

Recombinant Human Autotaxin/ENPP2 Protein (aa 36-863, His Tag)

Product Code:
 
PKSH033693
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033693-10ug10ug£180.00
Quantity:
PKSH033693-50ug50ug£378.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Autotaxin;ENPP2
Accession:
Q13822
Background:
ENPP-2, also known as Autotaxin, belongs to the ectonucleotide pyrophosphatase/phosphodiesterase (NPP) family. Some NPPs hydrolyze phosphates from nucleotides and their derivatives. ENPP-2 shares 40 - 50% identity to ENPP1 & 3, all of which contain a N-terminal intracellular domain, a single transmembrane domain and a large extracellular domain that includes a catalytic domain, two somatomedin-B-like domains, and a C-terminal nuclease-like domain.Evidence shows LPA and sphingosine 1-phosphate to be specific inhibitors of ENPP-2. ENPP-2 was originally found to stimulate tumor cell motility and has since been found to enhance tumor invasion and metastasis and to be up-regulated in several types of carcinomas including breast and lung.
Calculated MW:
90 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mMPB,150mMNaCl,pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
100-120 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Ala36-Ile863
Target Synonym:
ATX;ATXFLJ26803;ATX-X;Autotaxin;autotaxin-t;EC 3.1.4.39;ectonucleotide pyrophosphatase/phosphodiesterase 2;E-NPP 2;ENPP2;LysoPLD;NPP2;PD-IALPHA;PDNP2;PDNP2NPP2
UNIProt ID:
Q13822

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