Elabscience

Recombinant Human GITR/TNFRSF18 Protein (mFc Tag)

Product Code:
 
PKSH033668
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033668-10ug10ug£170.00
Quantity:
PKSH033668-50ug50ug£315.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
GITR;TNFRSF18
Accession:
Q9Y5U5
Background:
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA, isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1; TRAF2; and TRAF3; but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.
Calculated MW:
41.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-mFc
ObservedMW:
40-55 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Gln26-Glu161(Thr45Ala)
Target Synonym:
Tumor necrosis factor receptor superfamily member 18;TNFRSF18;Glucocorticoid-induced TNFR-related protein;CD357;TNFRSF18;AITR;GITR
UNIProt ID:
Q9Y5U5

Documents