Elabscience

Recombinant Human TIM-3/HAVCR2 Protein (His Tag)(Active)

Product Code:
 
PKSH033509
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSH033509-10ug10ug£146.00
Quantity:
PKSH033509-50ug50ug£277.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
TIM-3;HAVCR2
Accession:
Q8TDQ0
Activity:
Immobilized Human Galectin-9-GST at 2ug/ml(100 ul/well) can bind Human TIM-3-His.
Background:
T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21); an extracellular region (aa 22-202) with one Ig-like V-type domain; a transmembrane segment (aa 203-223); and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation; inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
Calculated MW:
20.86 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
37 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser22-Arg200 (Arg140Leu)
Target Synonym:
Hepatitis A Virus Cellular Receptor 2;HAVcr-2;T-Cell Immunoglobulin and Mucin Domain-Containing Protein 3;TIMD-3;T-Cell Membrane Protein 3;TIM-3;HAVCR2;TIM3;TIMD3
UNIProt ID:
Q8TDQ0

Documents