Elabscience

Recombinant Human TRAIL Protein (His Tag) (Active)

Product Code:
 
PKSH033422
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Cell Culture
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSH033422-20ug20ug£210.00
Quantity:
PKSH033422-100ug100ug£472.00
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This product comes from: China.
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Further Information

Abbreviation:
TRAIL
Accession:
P50591
Activity:
Measure by its ability to induce cytotoxicity in L929 cells in the presence of actinomycin D. The ED50 for this effect is 10.4-15.4 ng/mL.
Background:
Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ?TNF homology domain? (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.
Calculated MW:
19.5 kDa
Endotoxin:
< 0.1 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from filtered solution of 1xPBS,pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
16 kDa
Purity:
> 98 % as determined by reducing SDS-PAGE.
Sequence:
Arg115-Gly281
Target Synonym:
Tumor Necrosis Factor Ligand Superfamily Member 10;Apo-2 Ligand;Apo-2L;TNF-Related Apoptosis-Inducing Ligand;Protein TRAIL;CD253;TNFSF10;APO2L;TRAIL
UNIProt ID:
P50591

Documents