Elabscience

AF/LE Purified Anti-Mouse CD8a Antibody[53-6.7]

Product Code:
 
E-AB-F11040
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clone:
 
53-6.7
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Blocking
  • Depletion
  • Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C. Do not freeze.
 

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CodeSizePrice
E-AB-F11040-50ug50ug£127.00
Quantity:
E-AB-F11040-500ug500ug£240.00
Quantity:
E-AB-F11040-1mg1mg£374.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
CD8a
Background:
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Buffer:
0.2 um filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration:
0.5 mg/mL
Conjugation:
None (Purified antibody-Azide Free/Low endotoxin)
GeneID:
12525
Target Synonym:
T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
UNIProt ID:
P01731
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 2.0 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

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