Elabscience

XIAP Polyclonal Antibody

Product Code:
 
E-AB-64526
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Immunofluorescence (IF)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of HeLa cells using XIAP Polyclonal Antibody
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Immunofluorescence analysis of HeLa cells using XIAP Polyclonal Antibody

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E-AB-64526-60uL60uL£210.00
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E-AB-64526-120uL120uL£291.00
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E-AB-64526-200uL200uL£431.00
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  • Further Information
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Further Information

Abbreviation:
XIAP
Background:
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human XIAP (NP_001158.2).
Purification method:
Affinity purification
Target Synonym:
XIAP;API3;BIRC4;IAP-3;ILP1;MIHA;XLP2;hIAP-3;hIAP3
UNIProt ID:
P98170

Documents

References

  • https://www.mdpi.com/1422-0067/22/11/5503