Elabscience

SSRP1 Polyclonal Antibody

Product Code:
 
E-AB-64763
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human esophageal cancer using SSRP1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Human esophageal cancer using SSRP1 Polyclonal Antibody at dilution of 1:100 (40x lens).

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E-AB-64763-60uL60uL£210.00
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E-AB-64763-120uL120uL£291.00
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E-AB-64763-200uL200uL£431.00
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Further Information

Abbreviation:
SSRP1
Background:
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
81kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human SSRP1 (NP_003137.1).
ObservedMW:
85kDa
Purification method:
Affinity purification
Target Synonym:
SSRP1;FACT;FACT80;T160
UNIProt ID:
Q08945

Documents