Elabscience

GDNF Polyclonal Antibody

Product Code:
 
E-AB-70291
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry analysis of paraffin-embedded mouse brain using GDNF Polyclonal Antibody at dilution of 1:300.
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Immunohistochemistry analysis of paraffin-embedded rat spinal marrow using GDNF Polyclonal Antibody at dilution of 1:200.
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Immunohistochemistry analysis of paraffin-embedded mouse brain using GDNF Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat spinal marrow using GDNF Polyclonal Antibody at dilution of 1:200.

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E-AB-70291-60uL60uL£184.00
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E-AB-70291-120uL120uL£251.00
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E-AB-70291-200uL200uL£351.00
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This product comes from: China.
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Further Information

Abbreviation:
GDNF
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
80 ug/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:500
Immunogen:
KLH conjugated Synthetic peptide corresponding to mouse GDNF
Purification method:
Affinity purification
Target Synonym:
Astrocyte derived trophic factor;Astrocyte derived trophic factor 1;Astrocyte-derived trophic factor;ATF 1;ATF 2;Atf;ATF1;ATF2;gdnf;GDNF;Glial cell derived neurotrophic factor;Glial Cell Line Derived Neurotrophic Factor;Glial cell line-derived neurotrophic factor;Glial derived neurotrophic factor;HFB1 GDNF;hGDNF;HSCR3
UNIProt ID:
Q07731,P48540

Documents