Elabscience

FOXO1 Polyclonal Antibody

Product Code:
 
E-AB-70143
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western Blot analysis of various samples using FOXO1 Polyclonal Antibody at dilution of 1:1000.
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Western Blot analysis of various samples using FOXO1 Polyclonal Antibody at dilution of 1:1000.

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CodeSizePrice
E-AB-70143-60uL60uL£184.00
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E-AB-70143-120uL120uL£251.00
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E-AB-70143-200uL200uL£351.00
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This product comes from: China.
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Further Information

Abbreviation:
FOXO1
Background:
FOXO1,also named as FOXO1A,FKHR and FKH1,is a member of the FOXO subfamily of Forkhead transcription factors. FOXO1 is a transcription factor which acts as a regulator of cell responses to oxidative stress. FOXO1 interacts with LRPPRC and SIRT1. In the presence of KIRT1,FOXO1 mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. FOXO1 contains three predicted protein kinase B phosphorylation sites (Thr-24,Ser-256,and Ser-319) that are conserved in other FOXO proteins. The t(2;13) and the variant t(1;13) translocations generate PAX3/FKHR and PAX7/FKHR fusion proteins respectively. The resulting protein is a transcriptional activator. Defects in FOXO1 are a cause of rhabdomyosarcoma type 2 (RMS2).
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
78-82kDa
Concentration:
0.58 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein corresponding to Mouse FOXO1
ObservedMW:
78kDa
Purification method:
Affinity purification
Target Synonym:
FKH 1;FKH1;FKHR;Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma);Forkhead box O1;Forkhead box protein O1;Forkhead box protein O1A;Forkhead in rhabdomyosarcoma;Forkhead;Drosophila;homolog of;in rhabdomyosarcoma;FoxO transcription factor;foxo1;FOXO1;FOXO1A;OTTHUMP00000018301
UNIProt ID:
Q9R1E0,G3V7R4

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