Elabscience

Connexin 43 Polyclonal Antibody

Product Code:
 
E-AB-70097
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry analysis of paraffin-embedded mouse heart  using Connexin 43 Polyclonal Antibody at dilution of 1:300.

Immunohistochemistry analysis of paraffin-embedded mouse heart  using Connexin 43 Polyclonal Antibody at dilution of 1:300.

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This product comes from: China.
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  • Further Information
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Further Information

Abbreviation:
Connexin 43
Background:
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
43kDa
Concentration:
0.53 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000, IHC 1:300-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43
ObservedMW:
43kDa
Purification method:
Affinity purification
Target Synonym:
Connexin 43;Connexin-43;Cx 43;Cx43;CXA1;DFNB38;Gap junction 43 kDa heart protein;Gap junction alpha-1 protein;Gap junction protein alpha 1 43kDa (connexin 43);Gap junction protein alpha 1 43kDa;Gap junction protein alpha like;GJA 1;Gja1;GJAL;ODD;ODDD;ODOD;SDTY3
UNIProt ID:
P17302,P23242,P08050

Documents

References

  • https://www.mdpi.com/1422-0067/23/9/4850
  • https://www.tandfonline.com/doi/abs/10.1080/10520295.2021.1962976