Recombinant Mouse TGFB2 Protein (Active)

TGFB2

P27090

Immobilized Mouse TGFB2 at 10ug/ml(100 ul/well) can bind Human TGFBR2-FC(Cat: PKSH033426). The ED50 of Mouse TGFB2 is 22ug/mL.

Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

12.7 kDa

< 1.0 EU per ug of the protein as determined by the LAL method.

HEK293 Cells

Lyophilized from a 0.2 um filtered solution of 4 mM HCl.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

None

25-28 kDa

> 95 % as determined by reducing SDS-PAGE.

Ala303-Ser414

TGFB2;BSC-1 cell growth inhibitor;Cetermin;Glioblastoma-derived T-cell suppressor factor;G-TSF;MGC116892;Polyergin;TGF-beta2;TGF-beta-2;transforming growth factor beta-2

P27090