Elabscience

Recombinant Human OX40/TNFRSF4 Protein (Fc Tag)(Active)

Product Code:
 
PKSH032843
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032843-10ug10ug£170.00
Quantity:
PKSH032843-50ug50ug£349.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
OX40;TNFRSF4
Accession:
P43489
Activity:
Immobilized Human OX40L-6His(Cat: PKSH032842) at 2ug/ml(100 ul/well) can bind Human OX40-Fc. The ED50 of Human OX40-Fc is 4. 23 ug/ml.
Background:
OX40;also termed CD134 and TNFRSF4; is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions; including cytokine production; expansion; and survival; are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance; peripheral T-cell homeostasis; and T-cell-mediated inflammatory diseases.
Calculated MW:
46.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
70 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Leu29-Ala216
Target Synonym:
Recombinant Human OX40/TNFRSF4 Protein (C-Fc)
UNIProt ID:
P43489

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