Elabscience

Recombinant Human MAN1B1 Protein (His Tag)

Product Code:
 
PKSH032400
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032400-10ug10ug£297.00
Quantity:
PKSH032400-50ug50ug£498.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
MAN1B1
Accession:
Q9UKM7
Background:
Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period.
Calculated MW:
68.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 50mM Tris-HCl,10mM reduced Glutathione,pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
68 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asp106-Ala699
Target Synonym:
Endoplasmic Reticulum Mannosyl-Oligosaccharide 1;2-Alpha-Mannosidase;ER Alpha-1;2-Mannosidase;ER Mannosidase 1;ERMan1;Man9GlcNAc2-Specific-Processing Alpha-Mannosidase;Mannosidase Alpha Class 1B Member 1;MAN1B1
UNIProt ID:
Q9UKM7

Documents