Elabscience

Recombinant Human BTLA/CD272 Protein (Fc Tag)(Active)

Product Code:
 
PKSH032104
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
The product is shipped on dry ice/blue ice. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032104-10ug10ug£500.00
Quantity:
PKSH032104-50ug50ug£777.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
BTLA;CD272
Accession:
Q7Z6A9
Activity:
Immobilized Human BTLA-Fc at 2ug/ml(100 ul/well) can bind Human HVEM-His(Cat: PKSH033657).
Background:
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.
Calculated MW:
40.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
55 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Lys31-Leu150
Target Synonym:
B- and T-Lymphocyte Attenuator;B- and T-Lymphocyte-Associated Protein;CD272;BTLA
UNIProt ID:
Q7Z6A9

Documents