REN Polyclonal Antibody

REN

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

0.3 mg/mL

Unconjugated

IHC 1:50-1:200

Recombinant protein of human REN

Affinity purification

Angiotensin forming enzyme;Angiotensin forming enzyme precursor;Angiotensinogenase;Angiotensinogenase precursor;FLJ10761;HNFJ2;REN;Ren1;RENI;Renin;Renin precursor renal

P00797