Elabscience

MCM6 Polyclonal Antibody

Product Code:
 
E-AB-14210
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human esophagus cancer using MCM6 Polyclonal Antibody at dilution of 1:60
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Immunohistochemistry of paraffin-embedded Human colon cancer using MCM6 Polyclonal Antibody at dilution of 1:60
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Immunohistochemistry of paraffin-embedded Human esophagus cancer using MCM6 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human colon cancer using MCM6 Polyclonal Antibody at dilution of 1:60

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E-AB-14210-20uL20uL£125.00
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E-AB-14210-60uL60uL£172.00
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E-AB-14210-120uL120uL£237.00
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E-AB-14210-200uL200uL£344.00
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Further Information

Abbreviation:
MCM6
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
93kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human MCM6
Purification method:
Affinity purification
Target Synonym:
DNA replication licensing factor MCM6;MCG40308;Mcm6;MCM6 minichromosome maintenance deficient 6 (MIS5 homolog;S. pombe);MCM6 minichromosome maintenance deficient 6;MCM6;Minichromosome maintenance complex component 6;Minichromosome maintenance deficient (mis5 S. pombe) 6;Minichromosome maintenance deficient 6 homolog;Minichromosome maintenance protein 6;Mis5;MIS5 homolog;p105MCM
UNIProt ID:
Q14566

Documents