Elabscience

KCNQ1 Polyclonal Antibody

Product Code:
 
E-AB-15154
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
1 / 2
Western Blot analysis of Mouse heart tissue using KCNQ1 Polyclonal Antibody at dilution of 1:200
2 / 2
Immunohistochemistry of paraffin-embedded Human breast cancer using KCNQ1 Polyclonal Antibody at dilution of 1:50
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Western Blot analysis of Mouse heart tissue using KCNQ1 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human breast cancer using KCNQ1 Polyclonal Antibody at dilution of 1:50

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E-AB-15154-20uL20uL£125.00
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E-AB-15154-60uL60uL£172.00
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E-AB-15154-120uL120uL£237.00
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E-AB-15154-200uL200uL£344.00
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Further Information

Abbreviation:
KCNQ1
Background:
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
75kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human KCNQ1
Purification method:
Affinity purification
Target Synonym:
ATFB1;ATFB3;FLJ26167;IKs producing slow voltage-gated potassium channel subunit alpha;IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1;Jervell and Lange-Nielsen syndrome 1;JLNS1;KCNA8;KCNA9;KCNQ1;KCNQ1;kidney and cardiac voltage dependend K+ channel;KQT-like 1;Kv1.9;Kv7.1;KVLQT1;long (electrocardiographic) QT syndrome;Ward-Romano syndrome 1;LQT;LQT1;Potassium channel;voltage-gated;shaker-relatd subfamily;member 9;Potassium voltage-gated channel subfamily KQT member 1;potassium voltage-gated channel;KQT-like subfamily;member 1;RWS;slow delayed rectifier channel subunit;SQT2;Voltage-gated potassium channel subunit Kv7.1;WRS
UNIProt ID:
P51787

Documents