IKBIP Polyclonal Antibody

IKBIP

IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

0.4 mg/mL

Unconjugated

IHC 1:50-1:200

Recombinant protein of human IKBIP

Affinity purification

FLJ31051;I kappa B kinase interacting protein;IKBIP;IKBKB interacting protein;IKIP1;IKIP2;IKIP3;IKK interacting protein;Inhibitor of nuclear factor kappa B kinase interacting protein

Q70UQ0