Elabscience

ABL1 Polyclonal Antibody

Product Code:
 
E-AB-10119
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human brain tissue using ABL1 Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human brain tissue using ABL1 Polyclonal Antibody at dilution 1:40

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E-AB-10119-20uL20uL£125.00
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E-AB-10119-60uL60uL£172.00
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E-AB-10119-120uL120uL£237.00
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E-AB-10119-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
ABL1
Background:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ABL1
Purification method:
Affinity purification
Target Synonym:
Abelson murine leukemia viral oncogene homolog 1;Abelson tyrosine protein kinase 1;Abl 1;ABL;ABL proto oncogene 1 non receptor tyrosine kinase;ABL1;ABL1;bcr/abl;bcr/c abl oncogene protein;c ABL;c abl oncogene 1 non receptor tyrosine kinase;c abl oncogene 1 receptor tyrosine kinase;c ABL1;JTK7;p150;Proto oncogene tyrosine protein kinase ABL1;Proto-oncogene c-Abl;Tyrosine-protein kinase ABL1;v abl Abelson murine leukemia viral oncogene homolog 1;v abl
UNIProt ID:
P00519

Documents