Elabscience

SLAMF7 Polyclonal Antibody

Product Code:
 
E-AB-68382
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using SLAMF7 Polyclonal Antibody at 1:3000 dilution.
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Western blot analysis of extracts of various cell lines using SLAMF7 Polyclonal Antibody at 1:3000 dilution.

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CodeSizePrice
E-AB-68382-60uL60uL£210.00
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E-AB-68382-120uL120uL£291.00
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E-AB-68382-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
SLAMF7
Background:
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed on the surface of NK cells, CD8+ T cells, activated B cells, and mature dendritic cells but not in promyelocytic, B-cell lines, or T-cell lines. In human NK cells, activated SLAMF7 transmits signals following association with the adaptor protein EAT-2 . In the absence of EAT-2, SLAMF7 potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
17kDa/21kDa/22kDa/25kDa/32kDa/37kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human SLAMF7
ObservedMW:
25-80KDa
Purification method:
Affinity purification
Target Synonym:
SLAMF7;19A;CD319;CRACC;CS1
UNIProt ID:
Q9NQ25

Documents