Elabscience

Rubicon Polyclonal Antibody

Product Code:
 
E-AB-90595
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of mouse brain using Rubicon Polyclonal Antibody at 1:3000 dilution.
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Western blot analysis of extracts of mouse brain using Rubicon Polyclonal Antibody at 1:3000 dilution.

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CodeSizePrice
E-AB-90595-60uL60uL£210.00
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E-AB-90595-120uL120uL£291.00
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E-AB-90595-200uL200uL£431.00
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Further Information

Abbreviation:
Rubicon
Background:
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
102kDa/103kDa/108kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human Rubicon
ObservedMW:
108kDa
Purification method:
Affinity purification
Target Synonym:
RUBCN;KIAA0226;RUBICON;SCAR15
UNIProt ID:
Q92622

Documents