Elabscience

(KO Validated) CD274 Polyclonal Antibody

Product Code:
 
E-AB-92259
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
1 / 2
Western blot analysis of extracts from normal (control) and CD274 knockout (KO) A-549 cells, using CD274 Polyclonal Antibody at 1:500 dilution.
2 / 2
Western blot analysis of extracts of various cell lines using CD274 Polyclonal Antibody at 1:500 dilution.
❮❯

Western blot analysis of extracts from normal (control) and CD274 knockout (KO) A-549 cells, using CD274 Polyclonal Antibody at 1:500 dilution.
Western blot analysis of extracts of various cell lines using CD274 Polyclonal Antibody at 1:500 dilution.

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CodeSizePrice
E-AB-92259-60uL60uL£224.00
Quantity:
E-AB-92259-120uL120uL£317.00
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E-AB-92259-200uL200uL£465.00
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This product comes from: China.
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Further Information

Abbreviation:
CD274
Background:
The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
32kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of mouse CD274
ObservedMW:
40-50KDa
Purification method:
Affinity purification
Target Synonym:
PD-; B7h1; Pdl1; Pdcd1l; Pdcd1l1; Pdcd1lg1; A530045L16Rik
UNIProt ID:
Q9EP73

Documents